Jehng-Kang Wang Selected Research

Enzyme Precursors (Zymogens)

7/2022	Differential subcellular distribution renders HAI-2 a less effective protease inhibitor than HAI-1 in the control of extracellular matriptase proteolytic activity.
1/2015	Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cells.
1/2014	Human cancer cells retain modest levels of enzymatically active matriptase only in extracellular milieu following induction of zymogen activation.
6/2010	TMPRSS2, a serine protease expressed in the prostate on the apical surface of luminal epithelial cells and released into semen in prostasomes, is misregulated in prostate cancer cells.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Jehng-Kang Wang Research Topics

Disease

7	Neoplasms (Cancer) 05/2022 - 06/2007
5	Carcinoma (Carcinomatosis) 01/2015 - 08/2008
3	Breast Neoplasms (Breast Cancer) 01/2020 - 01/2015
2	Burkitt Lymphoma (Burkitt's Lymphoma) 07/2022 - 10/2013
2	Inflammation (Inflammations) 05/2022 - 03/2011
2	Diarrhea 01/2021 - 01/2017
2	Inborn Genetic Diseases (Disease, Hereditary) 07/2020 - 01/2014
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 05/2022
1	Adenocarcinoma 01/2021
1	Ovarian Neoplasms (Ovarian Cancer) 01/2020
1	Basal Cell Carcinoma (Rodent Ulcer) 01/2020
1	Pituitary Neoplasms (Pituitary Adenoma) 01/2020
1	Neoplasm Metastasis (Metastasis) 01/2020
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2020
1	Ichthyosis (Xeroderma) 02/2014
1	autosomal recessive Ichthyosis with hypotrichosis 02/2014
1	Hyperplasia 10/2013
1	Lymphoma (Lymphomas) 10/2013
1	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 10/2013
1	Hypoxia (Hypoxemia) 10/2013
1	B-Cell Lymphoma (Lymphoma, B Cell) 10/2013
1	Skin Diseases (Skin Disease) 03/2011
1	Carcinogenesis 06/2010
1	Prostatic Neoplasms (Prostate Cancer) 06/2010
1	Leukemia 06/2007
1	Proteinuria 08/2003

Drug/Important Bio-Agent (IBA)

12	matriptaseIBA 07/2022 - 08/2008
5	HGF activatorIBA 01/2017 - 08/2008
4	Enzyme Precursors (Zymogens)IBA 07/2022 - 06/2010
4	Serine Proteases (Serine Protease)IBA 01/2014 - 08/2008
2	EnzymesIBA 07/2022 - 06/2010
2	SodiumIBA 01/2021 - 01/2017
2	BuffersIBA 01/2014 - 10/2013
2	Proteins (Proteins, Gene)FDA Link 01/2012 - 06/2010
2	Peptide Hydrolases (Proteases)FDA Link 03/2011 - 06/2010
1	andrographolideIBA 05/2022
1	Blood Glucose (Blood Sugar)IBA 05/2022
1	prostasinIBA 01/2021
1	Serine (L-Serine)FDA Link 01/2021
1	Filaggrin ProteinsIBA 07/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	Protease Inhibitors (Protease Inhibitor)IBA 10/2013
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2011
1	Carrier Proteins (Binding Protein)IBA 06/2010
1	DisulfidesIBA 06/2010
1	Phenobarbital (Luminal)FDA Link 06/2010
1	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 08/2008
1	p38 Mitogen-Activated Protein KinasesIBA 06/2007
1	Oxygen (Dioxygen)IBA 06/2007
1	anti-dsDNA autoantibodyIBA 08/2003
1	Antigen-Antibody Complex (Immune Complex)IBA 08/2003